Figure 14.
Microfluidic synthesis of silica-based biomaterials for drug delivery. (A) Microfluidic synthesis of mesoporous silica-solid lipid microcomposite for aqueous insoluble and aqueous soluble drugs delivery. Reproduced with permission from ref.103. (B) Schematic diagram of a capillary microfluidic system for generating the W/O/W double emulsion droplets, the fabrication process of the hierarchically porous composite microparticles for controllable drug delivery, the generation of microparticles-coated scaffold and its application in abdominal wall repair. Reproduced with permission from ref.122. (C) Schematics of the process to synthesize cell penetrating peptide-functionalized multidrug-loaded PSi@AcDX-CPP. Reproduced with permission from ref.111. (D) Drug release profiles of microfluidics-enabled one-step production of doxorubicin-loaded mesoporous silica fiber and two representative fluorescent images after drug release tests. Reproduced with permission from ref.57.