Chip-scale operations |
Yes |
Yes |
No |
Tunable parameters |
Yes, the design of microfluidic reactors and the adjustable flow rate provide flexible reactions |
No, the only adjustable parameter may be the stirring rate during the reaction |
Fast reaction |
Yes, generally takes seconds or less |
No, usually takes hours or days |
Precise control |
Yes, precise control over each step: seeding, growth and ceasing reaction |
No, lack control over seeding and growth |
Reproducibility |
Medium |
High |
Low |
Automation |
Yes, programmable equipment makes the process automatic |
No, usually require watching over the process |
Low consumption of reagents |
Yes, owing to the scale effect |
No |
Scale-up probability |
Low |
Moderate |
High, very easy to fabricate large quantity of products |
Low cost |
If scaled up, yes; otherwise no |
When large quantity of products required, yes; otherwise, moderate |
Harsh conditions |
Yes, with the enclosed environment |
No |
R&D Pilot Studies |
Very suitable for the development of new materials and/or material screening |
Not suitable, low efficiency and no precise control |