Table 2.

Silica materials synthesized from continuous laminar flow microreactors.

Microchannel type	Material type	Material size	Material shape	Porous type	Bioapplication Area	Ref by Year
Winding	SiO2	164–321 nm	Sphere	Solid	N/A	200439
Y junction	SiO2	362–825 nm	Sphere	Solid	GOD immobilization	200841
Coflow	Fe2O3@SiO2	50 nm	Sphere	Solid	N/A	200942
Y junction	SiO2	200–400 nm	Sphere	Mesopore (~2 nm)	N/A	201043
Slit interdigital	SiO2	50–300 nm	Sphere	Solid	N/A	201144
Cross junction-baffled mixer	SiO2	46–250 nm	Sphere	Solid	N/A	201145
Y junction	SiO2	53–176 nm	Sphere	Solid	N/A	201146
Slit interdigital	SiO2@Au	~80 nm	Sphere	Solid	N/A	201247
Winding-Spiral	Fe2O3@SiO2@Pt	85 nm	Sphere	Solid	IBA oxidation	201248
Y junction	SiO2@Au/Fe2O3	~200 nm	Sphere	Solid	N/A	201349
Central collision	SiO2@Au	~100 nm	Sphere	Solid	N/A	201550
Y junction	SiO2-TiO2	33 nm	Sphere	Solid	N/A	201551
Slit interdigital and T junction	SiO2	50–650 nm	Sphere	Hollow; mesopore (~3–4 nm)	N/A	201552
T-shaped	SiO2; Co3O4@ SiO2	~150–650 nm	Sphere	Solid	N/A	201753
Spiral	SiO2	80×150 nm	Ellipsoid	Hollow; mesopore (~3 nm)	Dox drug loading	201754
Flow-focusing	SiO2	30–80 nm	Sphere	Hollow	N/A	201755
Spiral	SiO2; SiO2-QDs/Fe3O4	~800 nm	Sphere	Hollow	Cell imaging; RB adsorption; Dox drug loading	201756
Spiral	SiO2; SiO2-Ag/Fe3O4	~130×1500 nm	Fiber	Mesopore (~3 nm)	Dox drug loading; 4-NP reduction	201857
Spiral	SiO2; SiO2-FeCo	~2 μm	Flower	Solid	CTC screening	201858
Spiral	Fe2O3@SiO2	~50–350 nm	Sphere; cube; rod; belt	Solid	CTC screening	201859
Spiral	SiO2	100 nm×15 μm	Sheet	Hollow; mesopore	RB, BSA, and Dox adsorption	201960
Spiral	Ag@SiO2	80×10 nm	Triangle	Solid	Cellular internalization	201961
Spiral	SiO2	1.2 μm	Sphere	Hollow; mesopore-macropore (2–100 nm)	4-NP reduction; BSA protein delivery	201962

Abbreviations: 4-NP: 4-nitrophenol; BSA: Bovine serum albumin; CTC: Circulating tumor cell; Dox: Doxorubicin; GOD: Glucose oxidase; IBA: 4-isopropyl benzaldehyde; N/A: Not Applicable; RB: Rhodamine B.