Table 5:
Attention | Habituation | Handling | Excitability | Regulation | Non-Optimal Reflexes | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Relevant phthalate mixture (27) | MEOHP MEHHP | MECPP MEP MMP | MECPP MEP MMP | MEOHP MCPP MEP | MEOHP MEP | MEOHP MCPP MEP | ||||||||||||
Source of Exposure | beta | 95% CI | p-value | beta | 95% CI | p-value | beta | 95% CI | p-value | beta | 95% CI | p-value | beta | 95% CI | p-value | beta | 95% CI | p-value |
PIV | 0.45 | −0.66, 1.56 | 0.419 | 0.64 | −0.59, 1.87 | 0.299 | 0.44 | −0.64, 1.52 | 0.419 | 0.51 | −0.57, 1.59 | 0.352 | 0.49 | −0.62, 1.60 | 0.383 | 0.45 | −0.63, 1.53 | 0.406 |
Invasive respiratory support | −0.53 | −0.53, 1.59 | 0.324 | 0.41 | −0.83, 1.65 | 0.512 | 0.89 | −0.12, 1.90 | 0.083 | 0.88 | −0.13, 1.88 | 0.086 | 0.64 | −0.40, 1.69 | 0.222 | 0.90 | −0.10, 1.90 | 0.077 |
Noninvasive respiratory support | 1.87 | 0.23, 3.52 | 0.026* | 2.30 | 0.53, 4.06 | 0.011* | 2.15 | 0.59, 3.71 | 0.008* | 2.05 | 0.49, 3.61 | 0.011* | 1.89 | 0.27, 3.52 | 0.023* | 2.01 | 0.45, 3.56 | 0.012* |
Feeding tube | −0.57 | −1.94, 0.81 | 0.412 | −0.42 | −1.89, 1.05 | 0.573 | −0.59 | −1.91, 0.72 | 0.370 | −0.53 | −1.84, 0.79 | 0.427 | −0.65 | −2.02, 0.71 | 0.341 | −0.55 | −1.86, 0.76 | 0.406 |
Central line | −0.71 | −2.00, 0.59 | 0.279 | −1.36 | −2.87, 0.14 | 0.076 | −0.48 | −1.71, 0.76 | 0.445 | −0.56 | −1.80, 0.67 | 0.365 | −0.48 | −1.77, 0.80 | 0.457 | −0.56 | −1.80. 0.68 | 0.368 |
Incubator | 1.16 | −0.04, 2.27 | 0.042* | 0.95 | −0.21, 2.12 | 0.107 | 0.85 | −0.24, 1.94 | 0.123 | 0.76 | −0.33, 1.85 | 0.169 | 1.04 | −0.08, 2.15 | 0.068 | 0.78 | −0.30, 1.86 | 0.153 |
p <0.05
- WQS regression analyses included 10 of 15 phthalate monoesters measured, all those measured above the limit of detection in greater than 85% of specimens collected from the cohort. Models adjusted for the following covariates: gestational age at birth, status as small for gestational age at birth, and infant gender.
- MEOHP = mono(2-ethyl-5-oxohexyl) phthalate; MEHHP = mono(2-ethyl-5-hydrohexyl) phthalate; MECPP = mono(2-ethyl-5-carboxypentyl) phthalate; MEP = monoethyl phthalate; MMP = monomethyl phthalate; MCPP = mono(3-carboxypropyl) phthalate