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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Mater Today (Kidlington). 2018 Apr 27;21(9):951–959. doi: 10.1016/j.mattod.2018.04.001

FIGURE 4.

FIGURE 4

Intraoperative photographs of NGCs (bright field/CFP fluorescence) at the surgical nerve repair site. Immediately before implantation, the sciatic nerve is exposed approximately 1.5 cm at its exit from the pelvis (yellow arrow: proximal segment; yellow arrowhead: distal segment). Following transection and implantation of the NGC (blue dotted outlines), the proximal and distal segments of the sciatic nerve is delicately inserted into the NGC and secured into position with tissue glue. 11 weeks after implantation, the proximal segment of the nerve can be seen to connect through the microchannels within the NGC (blue arrow). Note: All images were obtained at the same magnification. Apparent differences in nerve and NGC sizes at different time points are due to the surgical orientation of the animal at the time of surgery.