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. Author manuscript; available in PMC: 2019 May 28.
Published in final edited form as: J Am Chem Soc. 2018 May 21;140(21):6522–6526. doi: 10.1021/jacs.8b02650

Table 1.

Decarboxylative Trifluoromethylation: Initial Studiesa

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a

Performed with acid 3 (0.05 mmol), photocatalyst 1 (1 mol%), Cu source (20 mol%), bathophenanthroline (30 mol%), 2-tert-butyl-1,1,3,3-tetramethylguanidine (BTMG, 0.5 equiv), CF3 source (1.25 equiv), and H2O (30 equiv) in EtOAc (0.025 M).

b

Yields by 19F NMR analysis. Yields in parentheses are isolated yields.

c

The ligand 3,4,7,8-tetramethyl-1,10-phenanthroline was used on the Cu catalyst.