Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 28;9:7923. doi: 10.1038/s41598-019-44171-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Histological analysis of lymph nodes. HE-stained lymph nodes of wild-type (A) and lymphoid follicles is indicated by the arrows. HE-stained lymph nodes of RAG2-knockout swine (B). HE-stained metastatic lymph nodes of RAG2-knockout swine (C). Metastatic tumour cells are surrounded by a dotted line. Immunohistochemical analysis of GFP expression in RAG2-knockout swine with tumours (D). HE-stained lymph nodes of RAG2-knockout swine with metastatic tumour (E) and IHC analysis using an anti-GFP antibody (F). HE-stained lymph nodes of RAG2-knockout swine (G) and IHC analysis using an anti-GFP antibody (H). Immunohistochemical analysis of alpha SMA expression in lymph nodes of RAG2-knockout swine with (I) and without (J) a metastatic tumour. Immunohistochemical analysis of TGF-beta expression in lymph nodes of RAG2-knockout swine with (K) or without (L) a metastatic tumour. Immunohistochemical analysis of tenascin C expression in lymph nodes of RAG2-knockout swine with (M) and without (N) a metastatic tumour. The scale bar = 1 mm (A–D) and 250 µm (E–N).