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. 2019 May 22;9:398. doi: 10.3389/fonc.2019.00398

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Copyright © 2019 Zheng, Qi, Wu, Zhou, Yu, Li, Yu, Chen and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Knockdown of circPCMTD1 inhibited cells growth in vivo. (A)The relative expression level of circPCMTD1 in U251 and U118MG cells were detected by qRT-PCR. The U118MG cells had higher expression levels of circPCMTD1. (B) Representative images of xenografts tumor (five mice per group) in nude mice. Tumors from nude mice after injection of U118MG cells transfected with si-NC, si-circ-1 or si-circ-2. (C) Tumor volume was monitored from each group after 35 d. (D) Tumor weights were measured from each group after 35 d. All the data are shown as the mean ± S.D., ***P < 0.001.