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. 2019 May 28;9:7936. doi: 10.1038/s41598-019-44415-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Micro-CT images of the proximal tibia. Representative crosssectional micro-CT images of the proximal tibia. From left to right: female Cy/+ Sham rats, female Cy/+ OVX rats (present study, Table 2), and for visual comparison, a representative image from a 35-week-old male Cy/+ rat showing prominent cortical porosity (unpublished) that is absent from both Sham and OVX female Cy/+ rats in the present study.