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. 2019 May 28;10(6):414. doi: 10.1038/s41419-019-1635-9

Fig. 5. ZCCHC10 enhances cisplatin sensitivity of lung cancer cells with wtp53 through promoting p53 induction.

Fig. 5

a IC50 of cisplatin following overexpression or knockdown of ZCCHC10. The cells were treated with different concentration of cisplatin for 48 h. Cell viability was detected by MTT assay. b, c WB analysis of p53 protein after treatment with different concentration of cisplatin for 12 h (b), or with 20 μM of cisplatin for different times (c). *p ≤ 0.05; **p ≤ 0.01; ns: non-significance