Table 1.
Median-effect doses (IC50) of Delta-24-RGD in pHGG and DIPG cell lines
| Cell lines | IC50 (MOIs ± SD) | |
|---|---|---|
| pHGG | CHLA-03-AA | 10.22 ± 3.1 |
| PBT-24 | 0.8 ± 0.06 | |
| SF188 | 9.6 ± 0.5 | |
| SJ-GBM2 | 32 ± 7.1 | |
| CHLA-200 | 5 ± 0.06 | |
| DIPG | TP54 | 9.6 ± 3.1 |
| DIPG IV | 3.6 ± 1.8 | |
| TP80 | 39.7 ± 10.9 | |
| TP83 | 51.9 ± 13.7 | |
| TP84 | 68 ± 4.1 | |
| JHH-DIPG1 | 26.2 ± 1.5 | |
| JHH-DIPG16A | 9.6 ± 5.9 |
The IC50 value (MOIs) is the median-effect dose (dose affecting 50% of the cells, i.e., 50% survival). IC50 = 50% inhibitory concentration; MOI=multiplicity of infection