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. 2019 May 22;10:306. doi: 10.3389/fpsyt.2019.00306

Table 3.

Characteristics of methadone-maintained heroin-dependent smokers, and multiple binary logistic regression on the associations between levels of smoking and nicotine dependence and sexual dissatisfaction.

Variables Total sample (n = 459) Sexual dissatisfaction (n = 151) % OR(95%CI) P OR(95%CI) P
Level of smoking Light 117 28 23.9 1
Moderate 99 28 28.3 1.16(0.62,2.16) 0.641
Heavy 243 95 39.1* 1.80(1.08,3.02) 0.025
Level of nicotine dependence Mild 102 16 15.7 1
Moderate 69 17 24.6 1.39(0.60,3.25) 0.446
Severe 288 118 41.0* 3.27(1.78,6.03) <0.001
Sex** Male 324 120 37.0 1 1
Female 135 31 23.0* 0.47(0.25,0.88) 0.019 0.41(0.23,0.70) 0.001
Age (years) ≤39 246 49 19.9 1 1
>39 213 102 47.9* 3.03(1.78,5.17) <0.001 2.82(1.74,4.57) <0.001
Education years Primary school and below 51 19 37.3 1 1
Junior middle school 237 95 40.1 1.01(0.48,2.15) 0.978 1.27(0.64,2.54) 0.492
Senior high school and above 171 37 21.6* 0.42(0.19,0.95) 0.037 0.63(0.30,1.33) 0.227
Marital status*** Married 249 74 29.7 1 1
Non-married 210 77 36.7 1.39(0.84,2.30) 0.203 1.62(1.02,2.57) 0.039
Employment Yes 232 49 21.1 1 1
No 227 102 44.9* 2.96(1.82,4.81) <0.001 3.40(2.15,5.36) <0.001
Route of heroin administration Smoking 69 19 27.5 1 1
Injection 390 132 33.8 2.38(1.17,4.83) 0.017 2.27(1.20,4.33) 0.012
Duration of heroin use (years) ≤10 273 84 30.8 1 1
>10 186 67 36.0 1.23(0.75,2.04) 0.394 1.24(0.78,1.98) 0.361
Methadone dosage (mg/d) <70 255 71 27.8 1 1
≥70 204 80 39.2* 1.87(1.13,3.08) 0.015 1.13(0.72,1.76) 0.595
MMT duration (months) ≤24 231 70 30.3 1 1
>24 228 81 35.5 1.02(0.63,1.67) 0.923 1.49(0.95,2.35) 0.085
Depressive symptoms No 256 54 21.1 1 1
Yes 203 97 47.8* 3.08(1.88,5.05) <0.001 2.43(1.54,3.83) <0.001

*Comparisons between subgroups, P < 0.05.

**Collected via self-report, confirmed by patients’ treating psychiatrists, who had performed the physical examination for patients.

***“Married” included married and remarried; “Non-married” included never-married, separated, cohabitating, divorced, and widowed.