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. 2019 Mar 8;37(3):538–547. doi: 10.1007/s10637-019-00755-x

Table 2.

Study drug exposure

DTP (N = 25)
Number of cycles delivered
Median (range) for trastuzumab 14.5 cycles (3–36)
Median (range) for pertuzumab 14.5 cycles (0–34)
Median (range) for eribulin 10.0 cycles (3–34)
Relative dose intensity (%)
Median (range) for trastuzumab 97.1% (29.0–104.5)
Median (range) for pertuzumab 95.1% (0–104.5)
Median (range) for eribulin 96.4% (23.3–115.4)
Dose omissions*, n (%) 18 (72.0%)
Dose reductions, n (%) 6 (24.0%)
Dose delays, n (%) 4 (16.0%)
Dose interruptions**, n (%) 7 (28.0%)

*The same patients had several reasons

**The same patients had several adverse events