Figure 6.

The effect of spike-frequency adaptation on the suppressive wave. A, Maximum of wave suppression (across space and time) for different values of adaptation strength b (dynamic adaptation model, red squares) and ratio between excitatory and inhibitory synaptic time scales (static adaptation model, blue dots). The values of b range from 0 to 100 pA, and the values of τ_E range from 3 to 9 ms (while τ_I = 5 ms); both arrows point to an increase in the values of b and τ_E. On the x axes, we report the corresponding value of spontaneous excitatory firing rate. B–E, Suppressive wave for four parameter values (see associated symbols in A). E, Dashed green line indicates the beginning of the hyperpolarization period of the model response due to adaptation. The excitatory external drive is r_drive = 3.5 Hz for blue dots (b = 80 pA) and r_drive = 1.2 Hz for red squares (τ_E = τ_I = 5 ms), and the amplitude of the input is A = 10 Hz for both blue dots and red squares.