TABLE 1.

The permeability-surface area product (PS) and cerebrovascular plasma volume (V_p) of ¹²⁵I-ApoA-I in various regions of rat brain at 60 minutes

Data represent mean ± S.D. (n = 6). ¹³¹I-ApoA-I was injected to serve as a measure of V_p. According to one-way ANOVA followed by Bonferroni post tests, the PS and V_p values for the brain stem and cerebellum are significantly greater (P < 0.05) than that of other regions.

Brain Region	PS	Vp
	ml/g per second × 10−6	µl/g
Cortex	0.39 ± 0.08	6.93 ± 0.59
Caudate putamen	0.28 ± 0.07	6.49 ± 0.93
Hippocampus	0.28 ± 0.07	6.94 ± 0.84
Thalamus	0.36 ± 0.12	9.45 ± 1.27
Brain stem	0.69 ± 0.22	14.37 ± 2.50
Cerebellum	0.76 ± 0.21	17.18 ± 3.38