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Representative time activity curves (TACs) and AUC (area under each TAC) for the different regions of interest (ROIs). (A) TACs extracted from the whole brain as ROI, and normalized by the injected activities and the body weight. Lines represent the [18F]UCB-H uptake over a 60 min acquisition after pre-treatment with the vehicle, SV2AL, SV2BL, or SV2CL. (B) The bar plots represent the AUC in the eight ROIs (mean ± SEM, n = 5).
