Figure 7.

Survival curves in rats that received cariporide, AVE4454B, or control solution at the start of chest compression during resuscitation from VF. Shown are survival curves for all rats and survival curves only for rats that had return of spontaneous circulation (ROSC) after defibrillation (Shocks). Top graphs depict survival for the individual interventions. Bottom graphs depict survival for the cariporide and AVE4454B groups combined (NHE-1 Inhibition). ∗ p < 0.01 vs. control by Gehan-Breslow analysis using Holm-Sidak’s test for multiple comparisons; ^† p = 0.01 vs. control by Gehan-Breslow analysis (adapted with permission from Radhakrishnan et al. [22]).