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Effects induced by test compounds on cell viability of HaCaT cells after stimulation with 5 ng/mL EGF (A, B) and A431 cells (C, D). Cells were exposed to compounds for 72 h and cell viability assessed by neutral red assay. Data are expressed as means ± SEM of three independent experiments, each performed in triplicate. Each hybrid was compared to single agents. D: diclofenac, HT: hydroxytyrosol, T: tyrosol.
