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. 2019 Apr 30;20(9):2130. doi: 10.3390/ijms20092130

Figure 4.

Figure 4

The modules in the mice subjected to exhaustive exercise stress (M) displaying a strong correlation with either blood urea nitrogen contents (BUN) (Module M03) or BUN to creatinine ratio (CR, Module M13) alone or both (Modules M02 and M21). The group N: healthy mice supplemented with PBS. The group M: mice subjected to exhaustive exercise stress supplemented with PBS. The group C: healthy mice supplemented with a daily dose of 150 mg/kg bodyweight of chondroitin sulfate disaccharide for 16 consecutive days. The group S: the stressed mice supplemented with a daily dose of 150 mg/kg bodyweight of CSD for 16 days. The detailed annotation of each OTU node can be found in Table S3.