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Silybin increases the cytotoxic effect of sorafenib. Effects of silybin (sil), sorafenib (sor) on AKT, GSK3 expression, in HepG2 cells transfected or not, with mutated PTEN (PTEN mut) was evaluated by Western blotting. γ-tubulin was used as loading control; standard deviation from the mean in at least three independent experiments.
