Table 5.
Evaluation of the interaction between the compounds and the active site of different α-glucosidases.
| Name | Consensus (Number of Votes) | Consensus (Normalized Average) | ||||||
|---|---|---|---|---|---|---|---|---|
| HPA | NtMGAM | CtMGAM | NtSI | HPA | NtMGAM | CtMGAM | NtSI | |
| 1-DNJ | 2 | 10 | 11 | 8 | 0.27 | 0.93 | 0.70 | 0.89 |
| DAB | 3 | 1 | 2 | 5 | 0.40 | 0.63 | 0.54 | 0.73 |
| Fagomine | 2 | 5 | 1 | 3 | 0.38 | 0.74 | 0.55 | 0.62 |
| acarbose | 11 | 7 | 10 | 7 | 0.93 | 0.62 | 0.84 | 0.75 |
| Miglitol | 5 | 11 | 10 | 6 | 0.35 | 0.81 | 0.67 | 0.76 |
Note: 1-DNJ, 1-deoxynojirimycin; DAB, 1,4-dideoxy-1,4-imino-d-arabinitol; HPA, pancreatic amylase; NtMGAM, maltase-glucoamylase N-terminal subunit; CtMGAM, maltase-glucoamylase C-terminal subunit; NtSI, sucrase-isomaltase N-terminal subunit