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General properties of ZINC04534268 and ZINC19370490.
| Properties | ZINC04534268 | ZINC19370490 |
|---|---|---|
| GI absorption | Low | Low |
| BBB permeant | No | No |
| P-gp substrate | No | Yes |
| CYP1A2 inhibitor | No | No |
| CYP2C19 inhibitor | No | No |
| CYP2C9 inhibitor | No | No |
| CYP2D6 inhibitor | No | No |
| CYP3A4 inhibitor | No | No |
| LogKp(skin permeation) | −6.67 cm/s | −14.17 cm/s |
