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. 2019 Apr 30;20(9):2155. doi: 10.3390/ijms20092155

Table 1.

Resveratrol increases NO production in endothelial cells.

Cell Type Effective Concentration Effects Reference
HUVEC 10–100 µM eNOS↑; NO↑ [48]
EA.hy 926 10–100 µM eNOS (via SIRT1/FOXO)↑; NO↑ [14,48]
HCAEC 1–100 µM eNOS (via SIRT1)↑ [13]
HUVEC 0.1 µM eNOS↑; VEGF↑; ET-1↓ [33]
BAEC, HUVEC 1–100 nM p-eNOS↑ (via ERα & Erk1/2) [24]
HUVEC 1–100 µM p-eNOS↑ (via AMPK) [54]
STA 50 µM p-eNOS↑ (via AMPK) [55]
RAEC 100 µM Ac-eNOS↓ [56]

Ac-eNOS; acetylated eNOS; BACE, bovine aortic endothelial cells; HCAEC, human coronary arterial endothelial cells; HUVEC, human umbilical vein endothelial cells; p-eNOS, phosphorylation of eNOS at serine 1177; STA, superior thyroid artery; RAEC, rat aortic endothelial cells; VEGF, vascular endothelial growth factor.