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. 2019 May 2;16:745–757. doi: 10.1016/j.omtn.2019.04.024

Figure 8.

Figure 8

Downregulation of miR-133b Induces Increased MAML1 Expression and Inactivated Notch-Signaling Pathway

(A) Relative expressions of miR-133b, Notch1, Jagged-1, DLL4, Bax, Bcl-2, and Caspase-3, as detected by qRT-PCR. (B) Gray values of MAML1, Notch1, Jagged-1, DLL4, Bax, Bcl-2, and Caspase-3, as determined by western blot analysis. (C) Statistical analysis of the gray values in (B). *p < 0.05, compared with the blank group; #p < 0.05, compared with the AS group; the measurement data were presented as the mean ± SD; the experiment was repeated 3 times. miR-133b, microRNA-133b; MAML1, mastermind-like 1; DLL4, Delta-like ligand 4; Bcl-2, B cell lymphoma-2; AS, atherosclerosis.