NCT02965222.

Trial name or title	A study select top‐grade embryo by time‐lapse imaging
Methods	Randomised single‐blinded controlled trial
Participants	Inclusion criteria: women under 38 years of age; ≤ 2 cycles; transplantation cycle.
Interventions	Intervention: after injecting human chorionic gonadotrophin 38 to 40 hours, the participant's oocytes will be taken with ICSI, then placed in the time‐lapse. The oocytes will be IVF after 4 hours and will be stripped surrounding cumulus cell, then will be placed in the time‐lapse. The third day the top‐grade embryo will be selected by time‐lapse imaging. The cleavage pattern and time parameters for marker embryo development were recorded daily after insemination. Control: the development of the embryos at time‐lapse was recorded directly and was not disturbed by temperature changes.
Outcomes	Primary outcome: live birth Secondary outcomes include: clinical pregnancy
Starting date	December 2016
Contact information
Notes	Estimated completion: December 2018