NCT03164551.

Trial name or title	TICON‐Day 3, Time lapse versus conventional method in day 3 embryo culture and assessment (TICON)
Methods	Parallel randomised controlled trial
Participants	Includes: couples with <= 2 failed fresh IVF/ICSI embryo transfer cycles; age 18 to 40 years; BMI: 18 to 30 kg/m2; normal uterine cavity under ultrasound; participant and her husband/partner must have read and signed the informed consent form; at least 4 normally fertilised oocytes (2PN) in the current cycle.
Interventions	Intervention: GERI+ incubator Control: conventional incubator
Outcomes	Primary outcome: clinical pregnancy Secondary outcomes include: ongoing pregnancy, multiple pregnancy, ectopic pregnancy, spontaneous miscarriage
Starting date	April 2018
Contact information	Merck KGaA Communication Center: service@merckgroup.com
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