Table 3.
Top upstream regulators (and their predicted activation) in HDAC5 versus vector-only transduced UC cell lines.
| Rank | RT112 | VM-Cub-1 | SW1710 | UM-UC-3 |
|---|---|---|---|---|
| 1 | TNF (Inhibited) |
TNF (Inhibited) |
TNF (Activated) |
TNF (Inhibited) |
| 2 | SMARCA4 (not given) |
estrogen receptor (Inhibited) |
dexamethasone (not given) |
Lipopolysaccharide (Inhibited) |
| 3 | Tretinoin (Inhibited) |
TGFB1 (not given) |
TGFB1 (Activated) |
TGFB1 (not given) |
| 4 | Lipopolysaccharide (Inhibited) |
SMARCA4 (Inhibited) |
SMARCA4 (not given) |
IFNG (Inhibited) |
| 5 | beta-estradiol (not given) |
beta-estradiol (not given) |
IFNG (not given) |
IL1B (Inhibited) |