Table 2.

Genes whose expressions were upregulated signicantly when all of the cells or cells in individual cell types were considered. The genes meet the criteria of Fold Change (FC) > 2 (log₂ FC > 1) and p < 0.001.

Gene	All Cells log2 FC	p	CD4+ log2 FC	p	CD8+/NK log2 FC	p	Naïve log2 FC	p
FDXR	4.05	5.9 × 10−16	3.63	5.2 × 10−9	4.52	1.7 × 10−5	4.90	8.9 × 10−4
BBC3	4.00	0.0 × 10+00	4.23	4.2 × 10−29	3.44	1.6 × 10−18	4.34	2.3 × 10−20
CD70	2.99	2.6 × 10−9	4.17	2.8 × 10−6	1.75	1.1 × 10−2	2.58	1.1 × 10−1
AEN	3.15	6.1 × 10−30	3.31	2.3 × 10−17	2.83	1.8 × 10−6	3.06	1.2 × 10−8
FHL2	3.08	5.3 × 10−4	2.95	7.9 × 10−3	2.29	1.5 × 10−1
PCNA	2.94	0.0 × 10+00	3.20	6.1 × 10−25	3.53	2.8 × 10−14	2.04	2.9 × 10−7
DDB2	2.87	0.0 × 10+00	3.17	1.5 × 10−21	2.82	7.3 × 10−11	2.49	4.0 × 10−12
GADD45A	2.79	1.5 × 10−15	2.66	6.0 × 10−9	5.64	1.3 × 10−4	1.47	1.9 × 10−2
ATF3	2.33	4.8 × 10−4	4.20	5.6 × 10−3	1.78	1.2 × 10−1	0.77	4.5 × 10−1
CDKN1A	2.08	3.6 × 10−4	3.65	6.0 × 10−4	0.23	8.1 × 10−1	0.77	6.6 × 10−1
TNFSF8	2.39	1.4 × 10−12	2.22	2.9 × 10−8	2.72	4.3 × 10−4	3.02	5.6 × 10−3
PHPT1	2.07	0.0 × 10+00	2.46	7.2 × 10−30	1.57	6.8 × 10−9	1.97	3.6 × 10−14
ACTA2	2.08	6.1 × 10−6	1.95	1.4 × 10−3	2.29	3.8 × 10−3
RPS27L	2.06	0.0 × 10+00	2.14	0.0 × 10+00	2.04	1.6 × 10−33	1.93	0.0 × 10+00
MDM2	1.95	7.0 × 10−8	1.46	1.7 × 10−3	4.67	1.6 × 10−3	1.70	1.9 × 10−2
TNFRSF10B	1.89	1.3 × 10−5	2.00	9.8 × 10−4	1.97	9.8 × 10−2	1.54	3.6 × 10−2
FAS	1.87	3.9 × 10−12	2.06	7.4 × 10−9	1.60	1.4 × 10−3	1.58	2.5 × 10−2
BAX	1.85	0.0 × 10+00	1.93	7.1 × 10−37	1.68	8.2 × 10−16	2.03	3.1 × 10−21
ASCC3	1.67	2.5 × 10−9	1.68	4.5 × 10−5	1.60	2.3 × 10−3	1.69	2.5 × 10−03
PRDM1	1.66	8.0 × 10−4	1.69	1.2 × 10−2	1.11	1.6 × 10−1
TRIAP1	1.62	1.2 × 10−17	1.85	1.3 × 10−10	1.66	3.3 × 10−5	1.19	2.7 × 10−4
FBXO22	1.52	1.5 × 10−7	1.95	3.6 × 10−5	1.55	2.2 × 10−2	1.02	2.3 × 10−2
ARHGEF3	1.50	6.5 × 10−9	0.92	1.1 × 10−2	2.34	3.5 × 10−4	1.90	8.4 × 10−5
TIGAR	1.50	3.6 × 10−5	1.30	1.2 × 10−2	1.25	5.4 × 10−2	2.36	1.1 × 10−2
STAT1	1.32	1.2 × 10−8	1.42	1.3 × 10−5	−0.27	6.9 × 10−1	1.55	3.3 × 10−5
APOBEC3C	1.39	4.2 × 10−7	1.41	1.3 × 10−3	1.65	1.4 × 10−4	0.99	1.1 × 10−1
XPC	1.33	3.8 × 10−14	1.22	9.0 × 10−7	0.92	6.7 × 10−3	1.99	1.9 × 10−7
SESN1	1.30	6.6 × 10−10	1.66	2.1 × 10−6	1.11	3.3 × 10−3	0.95	9.7 × 10−3
IKBIP	1.26	3.2 × 10−5	1.58	1.1 × 10−3	1.23	3.6 × 10−02	0.97	7.5 × 10−2
HDLBP	1.18	9.2 × 10−4	1.25	1.7 × 10−2	1.55	3.9 × 10−2	0.77	2.4 × 10−1
ZMAT3	1.15	1.8 × 10-04	1.45	1.2 × 10−03	0.80	1.8 × 10−1	0.77	2.1 × 10−1
TRIM22	1.15	1.5 × 10−10	1.04	1.4 × 10−5	1.52	5.2 × 10−4	1.07	2.0 × 10−3
BATF	1.08	2.7 × 10−4	1.44	6.7 × 10−4	0.05	9.3 × 10−1	1.77	1.1 × 10−2
IRF1	1.03	1.3 × 10−23	1.29	2.5 × 10−17	0.04	8.5 × 10−1	1.09	1.9 × 10−10
MAP4K4	1.01	1.8 × 10−4	0.73	4.7 × 10−2	1.19	9.1 × 10−2	1.44	3.9 × 10−3
NINJ1	0.91	2.7 × 10−06	1.22	7.3 × 10−5	0.71	5.2 × 10−2	0.67	5.8 × 10−2