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. 2019 May 10;20(9):2316. doi: 10.3390/ijms20092316

Table 4.

Z-value of the upstream regulators identified in each of the three clusters generated by Ingenuity Pathway Analysis (IPA). Significantly regulated genes were defined by fold>2.0 and p < 0.001. STAT1 and IRF1 had a Z value below 2 in only the CD8+/NK cells.

CD4+ CD8+/NK Naïve
TP53 4.51 3.8 3.58
TP63 2.96 2.44 2.58
NFATC2 2.35 1.11 1.91
STAT1 2.28 0.54 2.74
IRF1 2.19 1.09 2.36
TP73 2.15 2.57 1.51
STAT5B −2.61 −2.19 −2.22
STAT5A −2.14 −2.19 −2.2