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Effects of legumain on inflammatory phenotypes in human monocytes (Mo)/macrophages (Mϕ). The effects of legumain on the inflammatory phenotype of THP-1 monocyte-derived macrophages were assessed by immunoblotting. (A,B) CD68, MARCO, and arginase-1 were used as markers of macrophage differentiation, M1 macrophages, and M2 macrophages, respectively. β-Actin served as a loading control. A representative set of reproducible results are shown from five independent experiments.
