Figure 4.

Visual representation of rule % improvement vs actual eRule. “Actual eRule” label is directly beneath the bar representing the parameters or the actual dosing rule in clinical use. Other bars represent the comparison to different algorithmically derived dosing rule parameter choices. (A) Ibuprofen shows about 3% improvement in alert savings if the dosing rule is 5-15 mg/kg vs the actual eRule of 4-11 mg/kg. (B) Ursodiol shows significant improvement in alert reduction if the rule range is increased.