Table 4.
Biological pathways related to proteins involved in UBE2C network.
| KEGG Number | Cellular Process | Protein Gene |
|---|---|---|
| hsa04110 | Cell cycle | ATM, ATR, BUB1, BUB1B, CCNA2, CCNB1, CCNB2, CDC20, CDC25A, CDC25C, CDK1, CHEK1, E2F1, MAD2L1, ORC6, PLK1, TP53, TTK, CHEK2 |
| hsa04114 | Oocyte meiosis | AURKA, BUB1, CCNB1, CCNB2, CDC20, CDC25C, CDK1, MAD2L1, PLK1, SGOL1 |
| hsa04914 | Progesterone-mediated oocyte maturation | AURKA, BUB1, CCNA2, CCNB1, CCNB2, CDC25A, CDC25C, CDK1, MAD2L1, PLK1 |
| hsa04218 | Cellular senescence | ATM, ATR, CCNA2, CCNB1, CCNB2, CCNE1, CCNE2, CDC25A, CDK1, CHEK1, CHEK2, E2F1, FOXM1, MYBL2, TP53 |
| hsa04115 | p53 signaling pathway | ATM, ATR, CCNB1, CCNB2, CDK1, CDKN1A, CHEK1, CHEK2, GTSE1, MDM2, TP53 |
| hsa04120 | Ubiquitin mediated proteolysis | BRCA1, CDC20, UBE2C, UBE2S |
| hsa04068 | FoxO signaling pathway | ATM, CCNB1, CCNB2, CDKN1B, PLK1, PLK4 |
| hsa03030 | DNA replication | FEN1, RNASEH2A |
| hsa03440 | Homologous recombination | ATM, BRCA1, BRCA2, RAD54L |
| hsa01522 | Endocrine resistance | E2F1, TP53 |
| hsa03460 | Fanconi anemia pathway | ATR, BRCA1, BRCA2, UBE2T |
| hsa05200 | Pathways in cancer | BRCA2, CKS2, E2F1, TP53 |
| hsa04151 | PI3K-Akt signaling pathway | BRCA1, TP53 |
| hsa05202 | Transcriptional misregulation in cancer | ATM, TP53 |
| hsa03410 | Base excision repair | FEN1 |
| hsa05222 | Small cell lung cancer | CKS2, E2F1, TP53 |
| hsa05215 | Prostate cancer | E2F1, TP53 |
| hsa05226 | Gastric cancer | E2F1, TP53 |
| hsa05220 | Chronic myeloid leukemia | E2F1, TP53 |
| hsa05219 | Bladder cancer | E2F1, TP53 |
| hsa05214 | Glioma | E2F1, TP53 |
| hsa05218 | Melanoma | E2F1, TP53 |
| hsa05212 | Pancreatic cancer | BRCA2, E2F1, TP53 |
| hsa05224 | Breast cancer | BRCA1, BRCA2, E2F1, TP53 |
| hsa05223 | Non-small cell lung cancer | E2F1, TP53 |