Table 2.

Patient characteristics for NK cells and granulocytes for the validation set ¹.

NK cells
Patients contributing eligible granulocyte preparations/enrolled patients	SIRS (n = 18/22)	Sepsis (n = 15/23)
Patient characteristics
Age (years)	68.7 ± 15.0	71.5 ± 11.8
Sex (Male/Female)	13/5	7/8
SOFA score	6.3 ± 2.7	10.4 ± 2.0 ****
CRP (mg/L)	59 ± 38 2	323 ± 111 ****
Lactate (mmol/L)	1.6 ± 1.3 3	2.3 ± 1.7 4
WBC (cells/nL)	16.7 ± 5.9	18.6 ± 4.9
SIRS etiology
Abdominal surgery	n = 7	N.A.
Thoracic surgery	n = 4	N.A.
Vascular surgery	n = 2	N.A.
Polytrauma	n = 4	N.A.
Otolaryngology surgery	n = 1	N.A.
Septic focus
Abdominal	N.A.	n = 7
Pulmonal	N.A.	n = 5
Soft tissue	N.A.	n = 2
Urogenital	N.A.	n = 1
Granulocytes
	SIRS (n = 22/22)	Sepsis (n = 18/23)
Patient characteristics
Age (years)	66.3 ± 14.9	69.4 ± 13.3
Sex (Male/Female)	16/17	9/9
SOFA score	6.5 ± 2.9	10.8 ± 2.7 ****
CRP (mg/L)	59 ± 47 2	313 ± 123 ****
Lactate (mmol/L)	1.9 ± 2.0 5	2.9 ± 2.4 6 *
WBC (cells/nL)	16.7 ± 6.4	15.3 ± 5.9
SIRS etiology
Abdominal surgery	n = 8	N.A.
Thoracic surgery	n = 4	N.A.
Vascular surgery	n = 3	N.A.
Polytrauma	n = 6	N.A.
Otolaryngology surgery	n = 1	N.A.
Septic focus
Abdominal	N.A.	n = 8
Pulmonal	N.A.	n = 8
Soft tissue	N.A.	n = 1
Urogenital	N.A.	n = 1
Patients contributing both NK cells and granulocytes/enrolled patients	n = 18/22	n = 15/23

¹ Data are represented as mean ± standard deviation; ² For one patient, who contributed both cell types, CRP determination was under the limit of detection (< 2.9 mg/L); ³ For one out of 11 available lactate determinations, lactate levels were above 2 mmol/L; ⁴ For nine out of the 15 sepsis patients, lactate levels were below 2 mmol/L; ⁵ For three out of 15 available lactate determinations, lactate levels were above 2 mmol/L; ⁶ For ten out of the 18 sepsis patients, lactate levels were below 2 mmol/L; **** p < 0.0001, * p < 0.05 from Wilcoxon rank-sum test.