allo-HSCT |
allogeneic hematopoietic stem cell transplantation |
AML |
acute myeloid leukemia |
GVL |
graft-versus-leukemia |
NK |
Natural killer |
MRD |
minimal residual disease |
DLI |
Donor lymphocyte infusion |
ICIs |
immune checkpoint inhibitors |
HLA |
human leukocyte antigen |
TIGIT |
T-cell immunoreceptor with Ig and immunoreceptor tyrosine-based inhibition motif domains |
GVHD |
graft versus host disease |
OS |
overall survival |
Tregs |
T-regulatory cells |
CR |
complete remission |
KIRs |
killer immunoglobulin-like receptors |
PD-1 |
programmed cell death protein 1 |
CTLA-4 |
cytotoxic T-lymphocyte-associated protein 4 |
TIM-3 |
T-cell immunoglobulin and mucin domain-containing protein 3 |
LAG-3 |
lymphocyte activation gene 3 |
BTLA |
B- and T-lymphocyte attenuator |
MDSC |
myeloid-derived suppressor cell |
HVEM |
herpesvirus entry mediator |
BiKEs |
bispecific killer cell engagers |
TriKEs |
trispecific killer cell engagers |
MDS |
myelodysplastic syndromes |
CARs |
chimeric antigen receptors |
HSCs |
hematopoietic stem cells |
MICA |
MHC class I-related chain A |
ULBP1 |
UL16-binding protein 1 |
HSC_BM |
hematopoietic stem cells from bone marrow |
early HPC_BM |
hematopoietic progenitor cells from bone marrow |
CMP |
common myeloid progenitor cell |
GMP |
granulocyte monocyte progenitors |
MEP |
megakaryocyte-erythroid progenitor cell |
PM_BM |
promyelocyte from bone marrow |
MY_BM |
myelocyte from bone marrow |
PMN_BM |
polymorphonuclear cells from bone marrow |
PMN_PB |
polymorphonuclear cells from peripheral blood |
B-cells |
CD19+ B-cells |
NK cells |
CD56+ natural killer cells |
mDC |
CD11c+ myeloid dendritic cells |
pDC |
CD123+ plasmacytoid dendritic cells |
HMs |
hematological malignancies |
ML |
malignant lymphoma |
ALL |
acute lymphoblastic leukemia |
JAK |
Janus kinase |
IFN |
interferon |