Table 2.
Clinical chemistry parameters after dosing with CBD oil for two weeks. Cells in bold italics are significantly different from vehicle (One-Way ANOVA, indicated by *, or Kruskal-Wallis with appropriate post-hoc test). Data presented as mean ± SEM (n = 6/group).
| Vehicle | 61.5 mg/kg | 184.5 mg/kg | 615 mg/kg | |
|---|---|---|---|---|
| ALT | 40.0 ± 3.6 | 41.3 ± 14.8 | 32.3 ± 4.3 | 115.4 ± 51.2 |
| AST | 66.7 ± 6.7 | 74.7 ± 6.7 | 68.2 ± 3.9 | 157.0 ± 48.9 |
| ALP | 112.2 ± 3.5 | 112.7 ± 4.6 | 104.0 ± 2.0 | 113.2 ± 12.2 |
| GGT | 5.2 ± 0.3 | 4.0 ± 0.4 | 4.7 ± 0.2 | 5.0 ± 0.3 |
| Total Bilirubin | 0.1 ± 0.0 | 0.1 ± 0.02 | 0.23 ± 0.02 | 1.5 ± 0.7 * |