Effects of sgg-RB overexpression in the nervous system on male (A,C,E) and female (B,D,F) lifespans. Control B, sggB denote hybrid genotypes obtained as a result of crossing the corresponding lines with the driver line D4 inducing the lifelong expression of the transgenic construct in the nervous system (A,B), with the driver line D5 inducing the expression of the transgenic construct in the embryonic CNS (central nervous system) (C,D), and with the driver line D6 inducing the increasing expression of the transgenic construct in the adult nervous system with age (E,F). A full description of genotypes is given in the Materials and Methods section.