Figure 12.

Signs of degeneration in the nervous system of females with pan-neuronal sgg-RB overexpression. Control B, sggB denote hybrid genotypes obtained as a result of crossing the corresponding lines with the driver line D4 inducing the expression of transgenic constructs in the nervous system. A full description of genotypes is given in the Materials and Methods section. Representative transmission electron microscopy images of the Drosophila brain (A,B) and rhabdomeres (C,D) at the age of 3 days. An example of a degeneration sign in the neuron body (A, indicated by the red star); rhabdomeres with violated structure (C, lacuna is indicated by the red arrow) compared to the respective controls (B,D). Bar = 1 µm or 2 µm.