Table 1.
Survival | Analysis Parameter | Peripheral | p-Value | Coronary 1 | p-Value | ||
---|---|---|---|---|---|---|---|
Uncoated | rsv-Coated | Uncoated | rsv-Coated | ||||
3 days | n-value | 4 | 4 | 6 | 5 | ||
Injury score | 1.00 ± 1.41 | 0.00 ± 0.00 | 3.00 ± 0.00 | 2.60 ± 0.55 | |||
Inflammation score | 1.75 ± 0.50 | 0.50 ± 1.00 | 0.143 | 2.20 ± 0.45 | 1.67 ± 1.03 | 0.515 | |
Fibrin score | 2.00 ± 0.82 | 0.75 ± 0.50 | 0.114 | 3.60 ± 0.55 | 3.40 ± 0.89 | 0.999 | |
I + M (mm2) | 4.23 ± 1.15 | 4.01 ± 0.89 | 0.999 | 1.15 ± 0.23 | 1.25 ± 0.67 | 0.999 | |
Macrophages | 4.47 ± 1.22 | 2.36 ± 1.42 | 0.013 * | 1.62 ± 0.38 | 2.28 ± 1.38 | 0.400 | |
% Reendothelialization | 61 ± 13 | 96 ± 4 | 0.029 * | 63 ± 18 | 29 ± 12 | 0.019 * | |
Neovascularization | 16.67 ± 4.21 | 9.82 ± 2.28 | 0.029 * | 38.79 ± 7.73 | 41.92 ± 7.14 | 0.792 | |
7 days | n-value | 4 | 4 | 6 | 5 | ||
Injury score | 1.00 ± 1.41 | 0.25 ± 0.50 | 3.00 ± 0.00 | 2.20 ± 1.30 | |||
Inflammation score | 1.75 ± 0.71 | 1.00 ± 0.82 | 0.486 | 2.33 ± 0.52 | 1.83 ± 0.75 | 0.394 | |
Fibrin score | 1.50 ± 1.00 | 1.50 ± 0.58 | 0.999 | 3.33 ± 0.52 | 2.00 ± 1.22 | 0.033 * | |
I + M (mm2) | 3.76 ± 1.22 | 3.23 ± 0.22 | 0.343 | 1.14 ± 0.23 | 1.48 ± 0.76 | 0.792 | |
Macrophages | 5.04 ± 1.17 | 3.09 ± 0.38 | 0.029 * | 1.49 ± 0.44 | 1.64 ± 1.33 | 0.931 | |
% Reendothelialization | 86 ± 18 | 99 ± 1 | 0.114 | 88 ± 7 | 81 ± 18 | 0.879 | |
Neovascularization | 23.77 ± 2.38 | 17.33 ± 6.12 | 0.114 | 28.51 ± 4.99 | 32.52 ± 9.02 | 0.537 | |
28 days | n-value | 7 | 7 | 12 | 12 | ||
Injury score | 0.14 ± 0.38 | 1.00 ± 1.31 | 2.08 ± 0.90 | 2.50 ± 0.52 | |||
Inflammation score | 0.29 ± 0.49 | 0.75 ± 1.04 | 0.511 | 1.27 ± 0.79 | 0.92 ± 0.79 | 0.214 | |
Fibrin score | 0.00 ± 0.00 | 0.50 ± 0.76 | 0.200 | 0.75 ± 0.62 | 0.58 ± 0.51 | 0.720 | |
I + M (mm2) | 4.01 ± 0.61 | 5.03 ± 1.09 | 0.073 | 2.25 ± 0.92 | 1.68 ± 0.53 | 0.151 |
1 Data pool of left anterior descending artery (LAD), left circumflex coronary artery (LCX), and right coronary artery (RCA).