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. 2019 May 9;20(9):2285. doi: 10.3390/ijms20092285

Table 1.

Summary of results. n-value: Number of arteries included; I + M: Intima–media area; Macrophages: Relative fluorescence of immunofluorescent-stained Mac-2; values are mean ± SD; p-value determined by Mann–Whitney test; * p ≤ 0.05.

Survival Analysis Parameter Peripheral p-Value Coronary 1 p-Value
Uncoated rsv-Coated Uncoated rsv-Coated
3 days n-value 4 4 6 5
Injury score 1.00 ± 1.41 0.00 ± 0.00 3.00 ± 0.00 2.60 ± 0.55
Inflammation score 1.75 ± 0.50 0.50 ± 1.00 0.143 2.20 ± 0.45 1.67 ± 1.03 0.515
Fibrin score 2.00 ± 0.82 0.75 ± 0.50 0.114 3.60 ± 0.55 3.40 ± 0.89 0.999
I + M (mm2) 4.23 ± 1.15 4.01 ± 0.89 0.999 1.15 ± 0.23 1.25 ± 0.67 0.999
Macrophages 4.47 ± 1.22 2.36 ± 1.42 0.013 * 1.62 ± 0.38 2.28 ± 1.38 0.400
% Reendothelialization 61 ± 13 96 ± 4 0.029 * 63 ± 18 29 ± 12 0.019 *
Neovascularization 16.67 ± 4.21 9.82 ± 2.28 0.029 * 38.79 ± 7.73 41.92 ± 7.14 0.792
7 days n-value 4 4 6 5
Injury score 1.00 ± 1.41 0.25 ± 0.50 3.00 ± 0.00 2.20 ± 1.30
Inflammation score 1.75 ± 0.71 1.00 ± 0.82 0.486 2.33 ± 0.52 1.83 ± 0.75 0.394
Fibrin score 1.50 ± 1.00 1.50 ± 0.58 0.999 3.33 ± 0.52 2.00 ± 1.22 0.033 *
I + M (mm2) 3.76 ± 1.22 3.23 ± 0.22 0.343 1.14 ± 0.23 1.48 ± 0.76 0.792
Macrophages 5.04 ± 1.17 3.09 ± 0.38 0.029 * 1.49 ± 0.44 1.64 ± 1.33 0.931
% Reendothelialization 86 ± 18 99 ± 1 0.114 88 ± 7 81 ± 18 0.879
Neovascularization 23.77 ± 2.38 17.33 ± 6.12 0.114 28.51 ± 4.99 32.52 ± 9.02 0.537
28 days n-value 7 7 12 12
Injury score 0.14 ± 0.38 1.00 ± 1.31 2.08 ± 0.90 2.50 ± 0.52
Inflammation score 0.29 ± 0.49 0.75 ± 1.04 0.511 1.27 ± 0.79 0.92 ± 0.79 0.214
Fibrin score 0.00 ± 0.00 0.50 ± 0.76 0.200 0.75 ± 0.62 0.58 ± 0.51 0.720
I + M (mm2) 4.01 ± 0.61 5.03 ± 1.09 0.073 2.25 ± 0.92 1.68 ± 0.53 0.151

1 Data pool of left anterior descending artery (LAD), left circumflex coronary artery (LCX), and right coronary artery (RCA).