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Changes in dermal extracellular matrix components in the aging process.
| Photoaging | Components | Intrinsic Aging |
|---|---|---|
| Decreased and fragmented | Collagen | Decreased and fragmented |
| Abnormally accumulated (SE) | Elastic fiber | Decreased |
| Increased in SE region | Hyaluronic acid | Not changed |
| Increased | Total sulfated GAGs | Decreased |
| Increased in SE region | Versican | Not changed? |
| Not changed | Biglycan | Decreased |
| Decreased in SE region | Decorin | Not changed? |
GAG = glycosaminoglycan, SE = solar elastosis.
