Skip to main content
. 2019 May 7;20(9):2242. doi: 10.3390/ijms20092242

Figure 1.

Figure 1

Bronchobini®’s ingredients (BRO) reduced rhinovirus- (RV) induced cytokine and chemokine release. Mouse precision-cut lung slices (PCLS) were infected with rhinovirus (RV) or sham-infected with medium (Med) or UV-inactivated, replication-deficient RV (UV-RV) in the presence of BRO (dilution 1:10, 1:100, 1:1000) or vehicle control (Veh, dilution 1:10). Cytokine protein levels were measured by ELISA or mesoscale discovery (MSD) in culture supernatants 24 h p.i. and normalized to the respective total protein content. Scatter plots with bars show mean + SD for n = 3 independent experiments with individual plots showing the mean of two biological replicates (duplicate wells with two PCLS each) per experiment. Each experiment was performed with PCLS pooled from three mice. *; **; *** indicate significance with p ≤ 0.05; 0.01; 0.001 according to a one-way ANOVA with Sidak’s multiple comparison post-hoc test.