PCR |
polymerase chain reaction |
dNTP |
deoxyribonucleotide triphosphates |
dsDNA |
double stranded DNA |
ssDNA |
single stranded DNA |
qPCR |
quantitative polymerase chain reaction |
MFC |
multiparameter flow cytometry |
Ct |
threshold cycle |
dPCR |
digital polymerase chain reaction |
ddPCR |
droplet digital digital polymerase chain reaction |
CML |
chronic myeloid leukemia |
TKI |
tyrosine kinase inhibitor |
TFR |
treatment free remission |
MR |
molecular remission |
MR4 |
molecular remissionwith 4 logs of transcript reduction |
MR4.5 |
Molecular remissionwith 4.5 logs of transcript reduction |
ELN |
European Leukemia Net |
NCCN |
National Comprehensive Cancer Network |
rRQ-PCR |
replicate quantitative polymerase chain reaction |
MPN |
myeloproliferative neoplasms |
JAK2 |
janus kinase 2 |
CALR |
calreticulin |
ET |
essential thrombocythemia |
PMF |
primary myelofibrosis |
MRD |
minimal residual disease |
WT1 |
Wilms tumor gene |
HSCT |
hematopoietic stem cell transplantation |
APL |
acute promyelocytic leukemia |
PML |
promyelocytic leukemia |
RARa |
retinoic acid receptor alpha |
ATRA |
all trans retinoic acid |
IDH1/2 |
Isocitrate dehydrogenase 1/2 |
NPM1 |
nucleophosmin |
MDS |
Myelodysplastic syndromes |