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. 2019 May 10;20(9):2312. doi: 10.3390/ijms20092312

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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3MC induces hepatosteatosis in WT but not in Tiparp^−/− mice. (A) Gross liver images from corn oil- and 3MC-treated WT and Tiparp^−/− mice at day 6. (B) Oil Red O staining was conducted to visualize neutral fats. Gene expression levels of Cd36, (C), Fasn (D), Srebp1 (E), and Cpt1a (F). Data represent the mean ± SEM of inflammatory genes; n = 3. ^a p < 0.05 two-way ANOVA comparison between genotype-matched corn oil- and 3MC-treated mice followed by a Tukey’s post hoc test for multiple comparisons.