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. 2019 May 24;14:3799–3817. doi: 10.2147/IJN.S196453

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© 2019 Dong et al.

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Average body weight of each group versus the day after the first dose. No statistical difference was observed in the body weights among different groups (n=7 in NT, CP, NP groups, n=10 in Co [5 mg/kg], NS-S-L [5 mg/kg], NS-S-M [25 mg/kg] and NS-S-H [50 mg/kg] groups).

Abbreviations: NT, no treatment; CP, cosolvent placebo; NP, nanosuspension placebo; NS-S-L, NS-S of low dose; NS-S-M, NS-S of medium dose; NS-S-H, NS-S of high dose; NS-S, CZ48 nanosuspension with particle size of 197.22 ± 7.12 nm.