Table 6.

Tumor growth rate from the first day of dosing until day 11

Groups	Tumor growth rate until Day 11
NT (n=7)	0.192±0.049
CP (n=7)	0.157±0.048
NP (n=7)	0.191±0.052
Co (n=10, 5mg/kg)	0.181±0.064
NS-S-L (n=10, 5mg/kg)	0.130±0.030
NS-S-M (n=10, 25mg/kg)	0.084±0.030*#
NS-S-H (n=10, 50mg/kg)	0.010±0.003*#

Notes: *p<0.05 compared to placebo groups by ANOVA followed Tukey’s post hoc. ^#p<0.05 compared to cosolvent group by ANOVA followed Tukey’s post hoc.

Abbreviations: NT, no treatment; CP, cosolvent placebo; NP, nanosuspension placebo; NS-S-L, NS-S of low dose; NS-S-M, NS-S of medium dose; NS-S-H, NS-S of high dose; NS-S, CZ48 nanosuspension with particle size of 197.22 ± 7.12 nm.