Table 7.
Summary of significance testing by Kaplan–Meier survival analysis among different groups
| Survival comparison | ||||
|---|---|---|---|---|
| Co | NS-S-L | NS-S-M | NS-S-H | |
| CP | 0.0453 | - | - | - |
| NP | - | 0.0219 | 0.0002* | 0.2046 |
| Co | - | 0.0309 | 0.0011* | 0.4765 |
| NS-S-L | - | - | 0.0085* | 0.9646 |
| NS-S-M | - | - | - | 0.0167 |
Note: *p<0.01 for a 10-way comparison in Kaplan–Meier analysis.
Abbreviations: NT, no treatment; CP, cosolvent placebo; NP, nanosuspension placebo; NS-S-L, NS-S of low dose; NS-S-M, NS-S of medium dose; NS-S-H, NS-S of high dose; NS-S, CZ48 nanosuspension with particle size of 197.22 ± 7.12 nm.