Table 1.
Physical and chemical characterization of empty, SLM- and fluorescein isothiocyanate (FITC)-loaded PNM and MNM (Mean ± SD, n = 3).
| Sample | Average Diameter (nm) | PdI | Zeta Potential (mV) | EE% | LC% |
|---|---|---|---|---|---|
| PNM | 59.7 ± 0.1 | 0.06 ± 0.02 | −5.5 ± 0.6 | - | - |
| MNM | 60.2 ± 2.5 | 0.05 ± 0.01 | −4.7 ± 0.6 | - | - |
| SLM-PNM | 61.3 ± 6.0 | 0.10 ± 0.03 | −4.7 ± 0.5 | 93.0 ± 3.9 | 2.9 ± 0.2 |
| SLM-MNM | 61.5 ± 4.3 | 0.10 ± 0.03 | −4.3 ± 0.5 | 92.9 ± 5.3 | 2.9 ± 0.2 |
| FITC-PNM | 60.6 ± 2.1 | 0.05 ± 0.01 | −6.2 ± 0.3 | 95.3 ± 1.2 | 1.9 ± 0.1 |
| FITC-MNM | 63.3 ± 1.4 | 0.10 ± 0.01 | −5.9 ± 0.2 | 95.7 ± 1.2 | 1.9 ± 0.0 |
PNM: Polymeric nanomicelles; MNM: Mixed nanomicelles; SLM-PNM: Silymarin-loaded polymeric nanomicelles; SLM-MNM: Silymarin-loaded mixed nanomicelles; FITC-PNM: Fluorescein isothiocyanate polymeric nanomicelles; FITC-MNM: Fluorescein isothiocyanate mixed nanomicelles.