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Physical stability of SLM-loaded nanomicelles in simulated gastric fluid (GF) and simulated intestinal fluid (IF) (Mean ± SD, n = 3).
| GF | IF | |||
|---|---|---|---|---|
| Sample | Average Diameter (nm) | PdI | Average Diameter (nm) | PdI |
| SLM-PNM | 58.7 ± 1.1 | 0.12 ± 0.01 | 65.4 ± 2.2 | 0.20 ± 0.02 |
| SLM-MNM | 61.3 ± 0.8 | 0.11 ± 0.01 | 65.3 ± 1.4 | 0.13 ± 0.01 |
SLM-PNM: silymarin-loaded polymeric nanomicelles; SLM-MNM: silymarin-loaded mixed nanomicelles; GF: simulated gastric fluid; IF: simulated intestinal fluid; PdI: polydispersity index.
