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. 2019 Apr 30;24(9):1688. doi: 10.3390/molecules24091688

Table 7.

Apparent permeability coefficients (Papp) of free-SLM and SLM-loaded nanomicelles. (Mean ± SD, n = 3).

Sample Papp × 10−9 (cm/s) AP-BL Papp × 10−9 (cm/s) BL-AP Efflux Ratio
SLM-PNM 9.10 ± 0.14 6.11 ± 1.25 0.67 ± 0.15
SLM-MNM 140.90 ± 15.06 * 6.16 ± 1.75 0.04 ± 0.01 *
Free-SLM N.D. 17.29 ± 0.30 N.A.

SLM-PNM: Silymarin-loaded polymeric nanomicelles; SLM-MNM: Silymarin-loaded mixed nanomicelles; Free-SLM: Silymarin aqueous solution; N.D.: Not detected; N.A.: Not applicable. * p < 0.05 vs. SLM-PNM by Mann Whitney test.