Table II.
Experimental evidence of caprin-1-associated human malignancies.
| Type of cancer | Type of evidence | (Refs.) |
|---|---|---|
| Hepatocellular | Tissue microarray and IHC of specimens from 239 patients | (53) |
| Human HepG2 and Hep3B cell lines | (20,47) | |
| Osteosarcoma | Tissue microarray and IHC of specimens from 59 patients | (23) |
| Human SaOS-2 and U2OS xenograft model | (23,49) | |
| Breast | PET imaging study of SaOS-2/Caprin-1 vs. 143B model | (54) |
| Melanoma | Human MCF-7, T-47D and MDA-MB-231 vs. MCF-10A | (20,22,47) |
| Human BT-474 and MDA-MB-453 ×enograft model | (45) | |
| Proteomic analysis of human BLM melanoma cells | (55) | |
| Glioblastoma | Human C6 and U87MG glioma cell lines | (48) |
| Prostate | Human PC-3 and LnCaP cell lines | (20,47) |
| Cervical | Human HeLa cell line | (20,47) |
| Gastric | Tissue microarray and IHC of specimens from 262 patients | (56) |
| Human NUGC-3, HGC-27 and MGC80-3 cell lines | (20,56) | |
| Pancreatic | Human H1299 ×enograft model | (57) |
| Colon | Human PANC-1, BxPC3, S2-013, SUIT-2, COLO357, HPAF, MIA-Paca2, Capan2 and AsPC-1 cell lines | (20,58) |
| Leukemia | Human DLD-1, SW480 and HCT116 ×enograft model | (20,59) |
| Human U-937 and human leukemic Jurkat T cells | (20) |
IHC, immunohistochemistry; PET, positron emission tomography.