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Effect of dietary HON on daily food intake (A), initial and final body weight (B), adipose tissue weight (C), plasma leptin levels (D), and the activity of lipid-regulating enzymes in adipose tissue (E) in db/db mice. Male C57BL/KsJ-db/db mice were fed a normal diet with or without HON (0.02%, w/w), or PIO (0.01%, w/w) for 5 weeks (n = 10 per group). Data are presented as mean ± SE. * p < 0.05, ** p < 0.01, *** p < 0.001. CON; control group, PIO; pioglitazone, HON; honokiol.
